Although engineers are generally familiar with NSF/ANSI 61, applying it in real-world specifications can be complex. Compliance often extends beyond individual components to full system assemblies. As a result, certification must be evaluated at the system level rather than assumed from a single product listing.

The standard covers all wetted materials and the manufacturing facility itself; even compliant components may not qualify if assembled in a non-certified location. Because there are multiple factors to verify to meet NSF/ANSI 61 compliance, early-stage specification and thorough documentation review are essential. Maintaining NSF/ANSI 61 compliance also requires ongoing attention to ensure long-term safe and reliable potable water system performance.